PermeGear vertical glass diffusion cells, commonly referred to as the original Franz Cells, are essential tools in transdermal and topical permeation studies. These diffusion cells are designed to offer precise measurements by mimicking skin barrier properties, enabling researchers to evaluate drug absorption effectively. One of the defining features of PermeGear Franz Cells is the variety of standard orifice diameters ranging from 5mm to 25mm, with custom sizes available for specialized applications.

The orifice in a Franz Cell refers to the area at the top of the receptor chamber, where the membrane or device being tested is exposed. This design allows for consistent testing of various formulations or materials under controlled laboratory conditions. PermeGear diffusion cells offer corresponding receptor chamber volumes from 5ml to 20ml, catering to diverse research needs. To ensure secure and effective clamping, the system incorporates different joint types, including o-ring joints, flat ground joints, and flat flange joints.

With the inclusion of precision-engineered clamps, PermeGear vertical diffusion cells provide reliable and reproducible results. Their durability and compatibility with a wide range of membranes make them indispensable in pharmaceutical research, cosmetic testing, and material science. By facilitating robust permeation studies, these tools play a crucial role in advancing topical and transdermal delivery systems.