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Tissue Regeneration
{:en}Tissue regeneration is one of the most important aspects in the recovery of post-operation patients. The method of tissue regeneration has been used since more than 15 years ago, especially in Mouth surgery. At present, a process has been found that can support the formation of fibrin tissue in the tube. One of them is by developing at the physiological stage, without involving the presence of other blood components and without using reagents in extraction tubes. The process / phase is at the time of sample centrifugation. Ortoalresa has developed centrifuge that matches that function, namely Microcen
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[Insight] Determining Nitrogen Protein Content
{:en}The Kjeldahl method was introduced a hundred years ago as a method for determining the amount Nitrogen. Later this method has also been known in determining proteins in organic materials; even applied in determining Nitrogen in inorganic materials. This method was initially considered difficult and took a long time. But now, various experiments are applying this method has grown rapidly. One of the most effective, saves money and place, introduced the Protein Analyzer unit consisting of Digester block, Scrubber and Nitrogen Distiller. The Protein Analyzer unit applies the method steps Kjeldahl; destruction using block digester and neutralization
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[Insight] The Latest Nanocrystal Breakthrough in Drug Development
{:en}Nanocrystal is the latest breakthrough in the development of drugs which are classified as drugs that are difficult to dissolve in water. Nanocrystal has been shown to be preferred compared to using nanoparticles in drug-delivery. Nanocrystal is superior in terms of its production, a structure that is simpler and conforms to varying route releases. A recent study from Fernandes and the team compared the effectiveness of both (nanocrystal and nanoparticles) by conducting a release test using cell diffusion with varying kinetic models. Diffusion cells are very important tools that help in formulating
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[Remark] Fractioned Pre-Vacuum Autoclave
{:en}Autoclave, a machine that applies pressure and steam to reach and maintain a condition (temperature) in order to eliminate bacteria from the material to be sterilized. Materials that usually become objects of sterilization are laboratory equipment such as glassware, media in microbiology laboratories, and equipment such as lab coat. However, some samples have special material specifications. The selection of an autoclave sterilization system must be adjusted to the sample material to be sterilized. Samples that have a hollow, porous and multipurpose material are recommended to use autoclave which has a special system
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[Remark] Culture Media Preparator
{:en}The World of Sterilizing Sterilization with stirring, cooling and dispensing built-in Autoclave, a machine that applies pressure and steam (hot steam) to reach and maintain a condition (temperature) in order to eliminate bacteria from the material to be sterilized. The sterilization process is not only carried out on laboratory tools / equipment used during the experiment, but can be a step in experiments such as for example in media preparation, which is known in the field of microbiology and tissue culture. For media preparation functions, the autoclave used must be integrated for preparation, sterilization
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[Insight] Will You Continue Using Your Refrigerated Centrifuge?
{:en} One of the article in EU Regulation 517/2014 about fuorinated greenhouse gases, which is effectively started from January 1st 2020 prohibits the marketing of equipment containing gases with a Global Warming Potential (GWP) above 2,500. So gases as common as R 404 A (GWP of 3922) or R 507 (GWP of 3985) cannot be used for the manufacture of new equipment or for the recharging of existing equipment. This regulation comes from the transposition of the agreements reached in the convention on climate change held within the framework of the summit
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[Insight] Quality control: Determination of pesticides in cultivated products
{:en}In most cases, the pesticides used during cultivation disappear due to the effect of external agents, such as wind and rain. However, sometimes pesticides can be absorbed by the surface of the plant, remaining retained in the leaves and fruit, to later be ingested by the consumer. Because long-term exposure to pesticides has been linked to various acute and chronic human health problems, it is especially important to ensure that pesticides do not exceed the optimal limits in the final product of the production chain; process known as quality control. The
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Happy New Year from Alterlab Family
{:en}Dear all our beloved costumer, May the success fill up your life throughout the New Year. Happy New Year!{:}{:id}Dear all our beloved costumer, May the success fill up your life throughout the New Year. Happy New Year!{:}
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[Insight] What is canned food sterilization?
{:en}For the production of canned food -vegetables or animals- to be generated under good safety conditions and also these can be preserved at room temperature, they need to be sterilized. In addition, in the majority of regulatory bodies in all countries, the sterilization of food by autoclaving is a legal requirement to produce and market canned food. Food sterilization Canned food sterilization, also known as commercial sterilization, is a physical technique of preserving food that is hermetically packaged in a container and subjected to high temperatures for a time to completely destroy
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[Guide] How to Avoid Color Changes in Preserves or Ready Meals after Pasteurizing or Sterilizing Them
{:en}When cooking, pasteurizing or sterilizing food, it tends to lose its color intensity. The orange of a carrot or pumpkin or the red of a strawberry also declines somewhat. That’s normal. Whether our food loses more or less color depends, in part, on its acidity level, that is, on its pH. The pH of an ingredient indicates its degree of hydrogen ion concentration. The more acidic a food is, the lower its pH value. The vast majority of foods are on a pH scale between 3 and 7. recommendations If you
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[Remark] TERRA Food-Tech® Autoclaves
{:en}Discover our retort sterilizers and pasteurizers specifically designed for small and medium-sized preserved food producers, restaurateurs, chefs and for the food industry. Our vertical retorts are used to sterilize and pasteurize preserved food, they combine an user-friendly interface coupled with the latest sterilization technology. TERRA Food-Tech® compact retorts can both sterilize and pasteurize food products in cans, glass and plastic containers. It is a tool developed to improve the production capacity of small food producers and to facilitate R&D testing and quality control of the food and packaging industry. Intended
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[Insight] Water Activity to Determine The shelf Life of Food
{:en}Very often, if appropriate control is not carried out in advance, part of the water contained in food and pharma products is subject to the development of bacteria and mold. These microorganisms can determine the shelf life of food or drugs over time and therefore expiration, creating potential health risks for consumers. This fundamental parameter is called aW, water activity. Water activity (aW) is the amount of "free" or "available" water in a product compared to “bound" water, the value is ranging from 0 to 1.0. Pure water have activity value
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[Remark] Flash Titrator – Kjeldahl Nitrogen in Food
{:en}[vc_row][vc_column][vc_column_text] Total Kjeldahl nitrogen (TKN) is defined as the sum of the ammoniacal nitrogen and organic nitrogen that are transformed into ammonium sulfate after mineralization. The method (reference ICC 105/1) is applied to the determination of nitrogenous substances in cereals and products derived from them. “Nitrogenous substances” are understood as the content of nitrogenous compounds in the product analyzed, calculated by multiplying the corresponding nitrogen content, determined by the method described, by a conventional factor. The organic substances in the sample are oxidized with concentrated sulfuric acid in the presence of
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Welcoming 2025: A Message of Hope and Progress
{:en}[vc_row][vc_column][vc_column_text] As we bid farewell to the past year, we embrace the new one with optimism and determination. The beginning of 2025 is not just a transition on the calendar; it is a time to reflect on achievements, learn from challenges, and set aspirations for the future. In the world of laboratory science and technology, every year brings innovations that transform how we approach research, diagnostics, and quality control. Alterlab is proud to have been part of this progress, supporting laboratories with cutting-edge equipment and solutions tailored to their needs. The year of
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[insight] In Vitro Permeation Test Studies for Topical Drug Products
{:en}[vc_row][vc_column][vc_column_text] In vitro permeation tests (IVPT) are indispensable tools for evaluating the efficacy and safety of topical drug formulations. These tests provide a controlled environment to study how a drug permeates through the skin barrier, offering a cost-effective alternative to extensive clinical trials. By simulating human skin permeability, IVPT allows researchers to predict drug absorption and refine formulations for optimal therapeutic performance. Franz Diffusion Cells have become a gold standard in IVPT due to their ability to replicate the diffusion properties of the skin barrier accurately. These cells facilitate precise measurements of
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[remark] The Role of PermeGear Vertical Glass Diffusion Cells in Permeation Studies
{:en}[vc_row][vc_column][vc_column_text]PermeGear vertical glass diffusion cells, commonly referred to as the original Franz Cells, are essential tools in transdermal and topical permeation studies. These diffusion cells are designed to offer precise measurements by mimicking skin barrier properties, enabling researchers to evaluate drug absorption effectively. One of the defining features of PermeGear Franz Cells is the variety of standard orifice diameters ranging from 5mm to 25mm, with custom sizes available for specialized applications. The orifice in a Franz Cell refers to the area at the top of the receptor chamber, where the membrane
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[guide] Setting Up and Conducting Permeation Tests with Franz Diffusion Cells
{:en}[vc_row][vc_column][vc_column_text]Franz Diffusion Cells are widely used for assessing drug permeation in transdermal and topical formulations. Proper setup and execution are crucial to ensure accurate and reproducible results. Below is a detailed, step-by-step guide to conducting permeation tests with Franz Diffusion Cells: 1. Prepare the Receptor Solution and Fill the Receptor Chamber Begin by selecting the appropriate receptor solution. The solution must closely mimic physiological conditions to ensure reliable results. For hydrophilic drugs, phosphate-buffered saline (PBS) is commonly used. For lipophilic drugs, a mixture of solvents like ethanol-water may be necessary. Degas
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[insight] Optimizing Sample Preservation with Refrigerated Centrifuges
{:en}[vc_row][vc_column][vc_column_text]Refrigerated centrifuges are indispensable tools in laboratories that handle temperature-sensitive samples. They ensure that biological materials such as proteins, nucleic acids, and other biomolecules remain stable during high-speed separation processes. This feature is particularly critical in fields like molecular biology, clinical diagnostics, and pharmaceutical research, where even slight temperature fluctuations can lead to sample degradation and compromised results. One of the primary benefits of using refrigerated centrifuges is their ability to maintain a consistent low temperature, even during extended or high-intensity runs. By preventing heat buildup caused by rotor friction, these
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[remark] The New Feature: REI System (Rotor Easy to Install)
{:en}[vc_row][vc_column][vc_column_text]Ortoalresa introduces a game-changing feature for its Digicen 22 series centrifuges—the REI (Rotor Easy to Install) system, designed to make rotor installation and replacement quick, safe, and hassle-free. This innovative system allows users to securely lock the rotor in place without the need for additional tools. When it’s time for removal, the rotor can simply be lifted out of its position with ease. The ergonomic design of the REI system offers unmatched convenience, enabling one-handed operation. Installing a rotor takes only a few seconds—just place it on the motor axis, and
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[guide] Best Practices for Using the Digicen 22R to Optimize Sample Preservation
{:en}[vc_row][vc_column][vc_column_text]The Digicen 22R refrigerated centrifuge is designed to safeguard the integrity of temperature-sensitive samples while delivering precise and reliable results. To ensure optimal sample preservation and extend the lifespan of your centrifuge, adhering to the following best practices is essential: 1. Pre-Cool the Rotor and Chamber Before starting your centrifugation process, pre-cool the rotor and chamber to the desired temperature. This step is especially crucial for preserving biological samples like enzymes, proteins, and nucleic acids. Use the pre-cooling mode of the Digicen 22R to stabilize the temperature before loading the samples. 2. Use
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[insight] Particle Size Analysis and Its Impact on Product Quality
{:en}[vc_row][vc_column][vc_column_text]Particle size analysis is a critical factor influencing product quality across various industries, including pharmaceuticals, food, and cosmetics. The size and distribution of particles in raw materials determine key attributes such as texture, solubility, dissolution rate, and overall product performance. Consistency in particle size ensures uniformity in formulations and enhances the efficiency of production processes. One of the most widely used methods for particle size analysis is sieve analysis, which involves separating particles by size using a series of stacked sieves with varying mesh sizes. This method is valued for its
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[remark] Features and Benefits of the FTL-0200 Sieve Shaker
{:en}[vc_row][vc_column][vc_column_text]The FTL-0200 Sieve Shaker is a versatile and reliable solution for particle size analysis across various industries. Designed with robust construction, this device ensures durability and long-term performance, even under demanding laboratory conditions. Its advanced features make it an indispensable tool for ensuring consistency and accuracy in particle size distribution studies. One of the key features of the FTL-0200 is its adjustable amplitude and frequency settings, allowing users to tailor the shaking motion to suit different sample types. Whether analyzing fine powders or coarse granules, the FTL-0200 ensures precise and reproducible
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[guide] How to Perform Efficient Sieving with the FTL-0200
{:en}[vc_row][vc_column][vc_column_text]Efficient particle size analysis is essential for ensuring product quality and consistency in various industries. The FTL-0200 Sieve Shaker is designed to simplify the sieving process while delivering precise and reproducible results. Below is a step-by-step guide for achieving efficient sieving using the FTL-0200. Select Appropriate Sieve Sizes and Assemble the Stack Begin by choosing sieve sizes that correspond to your analysis requirements. Arrange the sieves in a stack, starting with the finest mesh at the bottom and the coarsest mesh at the top. Ensure that the sieves and the base
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[insight] The Critical Role of Moisture Content in Food and Pharmaceutical Industries
{:en}[vc_row][vc_column][vc_column_text]Moisture content plays a pivotal role in maintaining the quality and functionality of products in the food and pharmaceutical industries. Accurate moisture analysis not only ensures product stability but also compliance with stringent industry standards, ultimately safeguarding consumer satisfaction and safety. In the pharmaceutical industry, the moisture content of drugs significantly impacts their efficacy, stability, and shelf life. Excess moisture can lead to degradation of active ingredients, compromising the medication's therapeutic value. On the other hand, insufficient moisture can result in brittleness or improper dissolution of tablets, affecting drug delivery. Precise
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[remark] High-Speed and Precision in Moisture Analysis with M5-Thermo A64M
{:en}[vc_row][vc_column][vc_column_text]Accurate and efficient moisture analysis is essential across multiple industries, from pharmaceuticals to food processing. The M5-Thermo A64M Moisture Analyzer by Bel Engineering offers a perfect blend of speed and precision, making it an indispensable tool for laboratories and quality control units. Equipped with advanced halogen heating technology, the M5-Thermo A64M ensures rapid and uniform drying, leading to precise moisture content measurements. Its high-resolution sensors and robust software algorithms provide consistent and reliable results, even for complex samples. This makes the analyzer ideal for applications ranging from product development in R&D
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[guide] Accurate Calibration and Maintenance for Moisture Analyzers
{:en}[vc_row][vc_column][vc_column_text]Maintaining the accuracy and reliability of moisture analyzers is essential for consistent results in industries like pharmaceuticals, food processing, and materials testing. Proper calibration and maintenance ensure that your equipment operates at peak performance, minimizing errors and maximizing efficiency. Regular Calibration: To maintain accuracy, regularly calibrate your moisture analyzer using certified reference materials. This practice ensures precise measurements and compliance with industry standards. Calibration should be performed according to the manufacturer’s recommendations or more frequently in high-use environments. Routine Cleaning: Keeping the heating elements and sample pans clean after each
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[insight] Thermal Processing and Its Role in Material Science Research
{:en}[vc_row][vc_column][vc_column_text] Thermal processing is a foundational technique in material science, used to alter and enhance the physical and chemical properties of various materials. Through processes like sintering, annealing, and calcination, scientists can control microstructure, phase composition, and mechanical strength, enabling the development of materials tailored to specific applications. One of the key tools in thermal processing is the tube furnace. This equipment allows precise control over temperature and atmosphere, making it essential for experiments requiring high thermal stability and uniform heating. Tube furnaces are commonly used in the synthesis of ceramics, nanomaterials,
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[remark] High-Temperature Capabilities of Modern Tube Furnaces
{:en}[vc_row][vc_column][vc_column_text] Modern tube furnaces are indispensable in materials science, metallurgy, and ceramics research, offering precise and uniform heating essential for processes like sintering, annealing, and calcination. The Hobersal HTF SC series exemplifies this with its advanced design and capabilities. Key Features of the Hobersal HTF SC Series: High-Temperature Performance: Capable of reaching maximum temperatures up to 1,600°C, accommodating a wide range of high-temperature applications. Versatile Design: Available in diameters ranging from 20 mm to 120 mm and heating zones of 300 mm, 450 mm, 600 mm, and 800 mm, with options for
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[guide] Safe and Efficient Use of Tube Furnaces in Laboratory Settings
{:en}[vc_row][vc_column][vc_column_text] Tube furnaces are essential in laboratories for high-temperature processes like sintering, thermal analysis, and material treatment. For safe and efficient operation, it is crucial to begin by preheating the furnace gradually to the desired temperature. This controlled heating helps prevent thermal shock, which can damage both the furnace components and the test samples. Next, using proper personal protective equipment (PPE) is essential when handling hot materials. Heat-resistant gloves, face shields, and lab coats are necessary to prevent injuries from high temperatures. It's also important to position the furnace in a well-ventilated
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[remark] TLV-PD: Advanced Features of the SMART Autoclave
{:en}[vc_row][vc_column][vc_column_text] The TLV-PD autoclave represents the next generation of sterilization technology, designed with intelligent systems to meet the demands of modern laboratories. Equipped with real-time monitoring and automatic validation, the TLV-PD ensures each sterilization cycle runs efficiently and safely without manual intervention. This technology enhances productivity while upholding the highest safety standards. One of TLV-PD’s standout features is its customizable cycles, allowing users to tailor sterilization parameters based on load type and specific requirements. It also incorporates a highly effective super drying system, making it ideal for instruments that require a completely